Dena Aruta

The Role of the Gut-Lung Axis in the Development of Tuberculosis

LabRoots - February 16, 2019

A large proportion of current literature is on the gut microbiome, which has been proven an essential part of the immune system and homeostasis within the body. The gut microbiome has been divided into two major phyla--Firmicutes and Bacteroidetes, but it should be noted that there have been at least 10 different phyla that may have significant contributions to the microbiome. Three predominant genera have been identified--(1) Bacteroides, (2) Prevotella, and (3) Ruminococcus. Lung tissue was previously thought to be sterile and devoid of microorganisms, but research has shown that there are microbiota from the Firmicutes, Bacteroidetes, and Proteobacteria phyla similar to those in the gut. 

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